DOT Hazard Class

Class 6.1

Toxic (Poison)

49 CFR §173.132

Placard: White placard with skull-and-crossbones symbol

ERG entries

797

Divisions

—

Packing groups

I · II · III

Compat groups

—

Definition

A material, other than a gas, that is known to be so toxic to humans as to afford a hazard during transportation, or that in the absence of adequate data on human toxicity is presumed to be toxic to humans based on animal test criteria (oral, dermal, or inhalation LD50/LC50).

Primary hazards

Highly toxic — may be fatal if inhaled, swallowed, or absorbed through skin
Contact may cause burns to skin and eyes
Some may be combustible; may release toxic fumes on fire
Runoff may pollute waterways

Public safety response

Isolate spill or leak area for at least 50 m (150 ft) for liquids and 25 m (75 ft) for solids. Ventilate closed spaces before entering. Use positive-pressure SCBA and chemical protective clothing.

Common materials in this class

Pesticides (organophosphates, carbamates), cyanides, arsenic compounds, mercury compounds, aniline, nitrobenzene, phenol.

UN1613Hydrocyanic acid, aqueous solutions UN1654Nicotine UN1680Potassium cyanide, solid UN1051Hydrogen cyanide, stabilized UN2810Toxic liquid, organic, n.o.s.

Packing groups

I: Great danger — LD50 ≤ 5 mg/kg (oral) or ≤ 50 mg/kg (dermal), or LC50 ≤ 200 mL/m³ (dust/mist)
II: Medium danger
III: Minor danger

Special provisions / notes

Materials with an inhalation LC50 ≤ 200 ppm (Zone A) or ≤ 1000 ppm (Zone B) are also TIH — trigger the Green pages Initial Isolation and Protective Action Distances.

Definition

Primary hazards

Highly toxic — may be fatal if inhaled, swallowed, or absorbed through skin
Contact may cause burns to skin and eyes
Some may be combustible; may release toxic fumes on fire
Runoff may pollute waterways

Public safety response

Isolate spill or leak area for at least 50 m (150 ft) for liquids and 25 m (75 ft) for solids. Ventilate closed spaces before entering. Use positive-pressure SCBA and chemical protective clothing.

Common materials in this class

Pesticides (organophosphates, carbamates), cyanides, arsenic compounds, mercury compounds, aniline, nitrobenzene, phenol.

UN1613Hydrocyanic acid, aqueous solutions UN1654Nicotine UN1680Potassium cyanide, solid UN1051Hydrogen cyanide, stabilized UN2810Toxic liquid, organic, n.o.s.

Packing groups

I: Great danger — LD50 ≤ 5 mg/kg (oral) or ≤ 50 mg/kg (dermal), or LC50 ≤ 200 mL/m³ (dust/mist)
II: Medium danger
III: Minor danger

Special provisions / notes

Materials with an inhalation LC50 ≤ 200 ppm (Zone A) or ≤ 1000 ppm (Zone B) are also TIH — trigger the Green pages Initial Isolation and Protective Action Distances.